Healing & regenerative · Peptide
TB-500
Also known as Thymosin Beta-4 fragment
A fragment of a natural repair protein explored for tissue regeneration and flexibility.
Status as of 2026-07 · reclassification ≠ FDA approval · educational only, not medical advice.
The signal it sends
Regulates actin (a cell-structure protein), aiding cell migration to repair sites.
Benefits & effects studied
- Soft-tissue recovery interest
- Wound-healing signals
- Cardiac-repair research
Research state
Pre-clinical/early; limited human data. Not approved.
Dosing & pharmacokinetics
Typically 1–2× weekly subcutaneous in protocols. Half-life: Longer-acting than BPC-157.
Dosing information is educational only. TB-500 decisions belong with a licensed clinician — Jevity does not recommend or supply dosing.
History & discovery
First described early 2000s by Not well documented (parent protein thymosin beta-4 isolated by Allan Goldstein and colleagues; Tβ4 characterized 1981 by Low et al.) Origin: Derived from thymosin beta-4, a protein first isolated from calf thymus in the 1960s-1980s and later identified as an actin-binding molecule; early-2000s work showed its short actin-binding fragment reproduced repair effects, establishing TB-500 as a defined synthetic compound..
Molecular structure
A synthetic N-terminally acetylated peptide based on the actin-binding domain (LKKTETQ) of thymosin beta-4.
Frequently asked questions
Is TB-500 FDA-approved?
Not FDA-approved — research use only On Jevity's evidence scale, TB-500 is graded "Animal data only". Reclassification for compounding is not the same as FDA approval.
What is TB-500 used for?
A fragment of a natural repair protein explored for tissue regeneration and flexibility. Regulates actin (a cell-structure protein), aiding cell migration to repair sites. Studied effects include: Soft-tissue recovery interest; Wound-healing signals; Cardiac-repair research. This is educational information, not a recommendation to use it.
Is TB-500 legal in the UAE?
UAE / DHA status: Prescription-only via a DHA-licensed clinic; unsupervised import restricted
Is TB-500 banned in sport?
WADA status: Prohibited at all times
What is TB-500's Jevity Score?
TB-500 has a Jevity Score of 25/100 — a proprietary composite of evidence strength (2/10), regulatory clarity (3/10) and supply verifiability (3/10). It reflects how established and legitimate the compound is, not a recommendation.
TB-500 is prescription-only or research-only. A licensed clinician must evaluate whether it's appropriate for you.
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Educational information only — not medical advice, a diagnosis, or a recommendation to use any substance or therapy. Regulatory status changes; verify current rules and any personal decision with a licensed clinician. Jevity is operated by Upcapital Global FZCO, Dubai, UAE.