Jevity

Metabolic & weight · Peptide

AOD-9604

Also known as GH fragment 176-191

A growth-hormone fragment studied for fat metabolism without GH's growth effects.

58/ 100Jevity Score™
In human trials
Evidence strength7/10
Regulatory clarity5/10
Supply verifiability4/10
FDA · USNot FDA-approved; compoundable (removed Cat 2, Sep 2024)
WADA · sportVerify on current WADA list
UAE · DHAPrescription-only via a DHA-licensed clinic

Status as of 2026-07 · reclassification ≠ FDA approval · educational only, not medical advice.

The signal it sends

May stimulate fat breakdown (lipolysis) without raising blood sugar like full GH.

Benefits & effects studied

Research state

Human fat-loss evidence is weak. Not approved for weight loss.

Dosing & pharmacokinetics

Investigational. Half-life: Short.

Dosing information is educational only. AOD-9604 decisions belong with a licensed clinician — Jevity does not recommend or supply dosing.

History & discovery

First described 1990s-2000s by Metabolic Pharmaceuticals (Australia) Origin: Developed by Australian firm Metabolic Pharmaceuticals from the C-terminal fat-metabolizing fragment of human growth hormone (residues 176-191), stabilized by adding a tyrosine residue; it failed its Phase 2b weight-loss endpoint in 2007 but gained FDA GRAS status as a food ingredient in 2014..

Molecular structure

A modified 16-amino-acid fragment of human growth hormone (residues 176-191) with an added N-terminal tyrosine.

Molecular structure of AOD-9604
Structure · PubChem

Frequently asked questions

Is AOD-9604 FDA-approved?

Not FDA-approved; compoundable (removed Cat 2, Sep 2024) On Jevity's evidence scale, AOD-9604 is graded "In human trials". Reclassification for compounding is not the same as FDA approval.

What is AOD-9604 used for?

A growth-hormone fragment studied for fat metabolism without GH's growth effects. May stimulate fat breakdown (lipolysis) without raising blood sugar like full GH. Studied effects include: Fat-metabolism research; Cartilage-repair interest. This is educational information, not a recommendation to use it.

Is AOD-9604 legal in the UAE?

UAE / DHA status: Prescription-only via a DHA-licensed clinic

Is AOD-9604 banned in sport?

WADA status: Verify on current WADA list

What is AOD-9604's Jevity Score?

AOD-9604 has a Jevity Score of 58/100 — a proprietary composite of evidence strength (7/10), regulatory clarity (5/10) and supply verifiability (4/10). It reflects how established and legitimate the compound is, not a recommendation.

AOD-9604 is prescription-only or research-only. A licensed clinician must evaluate whether it's appropriate for you.

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Educational information only — not medical advice, a diagnosis, or a recommendation to use any substance or therapy. Regulatory status changes; verify current rules and any personal decision with a licensed clinician. Jevity is operated by Upcapital Global FZCO, Dubai, UAE.