Growth-hormone axis · Peptide
Ipamorelin
A selective growth-hormone-releasing peptide with a clean side-effect profile.
Status as of 2026-07 · reclassification ≠ FDA approval · educational only, not medical advice.
The signal it sends
Activates the ghrelin/GH-secretagogue receptor to release GH without big cortisol spikes.
Benefits & effects studied
- Recovery & body-composition interest
- Often paired with CJC-1295
Research state
Early human data; not approved.
Dosing & pharmacokinetics
1–3× daily subcutaneous in protocols. Half-life: ~2 hours.
Dosing information is educational only. Ipamorelin decisions belong with a licensed clinician — Jevity does not recommend or supply dosing.
History & discovery
First described mid-1990s by Novo Nordisk (Denmark) Origin: Developed by Novo Nordisk in the mid-1990s (as NNC 26-0161) as the first selective growth hormone secretagogue; derived from GHRP-1 by removing a central dipeptide and adding aminoisobutyric acid for stability. Novo Nordisk never filed it for approval..
Molecular structure
A synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) that acts as a ghrelin-receptor agonist.
Frequently asked questions
Is Ipamorelin FDA-approved?
Not FDA-approved; compoundable (removed from 503A Cat 2, Sep 2024) On Jevity's evidence scale, Ipamorelin is graded "Early / limited human data". Reclassification for compounding is not the same as FDA approval.
What is Ipamorelin used for?
A selective growth-hormone-releasing peptide with a clean side-effect profile. Activates the ghrelin/GH-secretagogue receptor to release GH without big cortisol spikes. Studied effects include: Recovery & body-composition interest; Often paired with CJC-1295. This is educational information, not a recommendation to use it.
Is Ipamorelin legal in the UAE?
UAE / DHA status: Prescription-only via a DHA-licensed clinic
Is Ipamorelin banned in sport?
WADA status: Prohibited at all times (GH axis)
What is Ipamorelin's Jevity Score?
Ipamorelin has a Jevity Score of 48/100 — a proprietary composite of evidence strength (4/10), regulatory clarity (6/10) and supply verifiability (5/10). It reflects how established and legitimate the compound is, not a recommendation.
Ipamorelin is prescription-only or research-only. A licensed clinician must evaluate whether it's appropriate for you.
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Educational information only — not medical advice, a diagnosis, or a recommendation to use any substance or therapy. Regulatory status changes; verify current rules and any personal decision with a licensed clinician. Jevity is operated by Upcapital Global FZCO, Dubai, UAE.