Sexual & hormonal · Peptide
Gonadorelin
Also known as GnRH
A natural-sequence GnRH used to stimulate the body's own hormone production.
Status as of 2026-07 · reclassification ≠ FDA approval · educational only, not medical advice.
The signal it sends
Pulses the pituitary to release LH/FSH, supporting testosterone/fertility pathways.
Benefits & effects studied
- Supports natural hormone production
- Used alongside some TRT protocols
Research state
Established clinical use for hormonal testing/fertility.
Dosing & pharmacokinetics
Pulsatile/periodic injection (clinician-determined). Half-life: Minutes.
Dosing information is educational only. Gonadorelin decisions belong with a licensed clinician — Jevity does not recommend or supply dosing.
History & discovery
First described 1971 by Andrew Schally and Roger Guillemin (independently) Origin: GnRH was independently isolated and sequenced in 1971 by Andrew Schally's team (from millions of porcine hypothalami) and Roger Guillemin's group (from ovine sources), guided by bioassays measuring LH release; the work earned them the 1977 Nobel Prize. Gonadorelin is the synthetic identical decapeptide..
Molecular structure
A decapeptide (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2) identical to natural gonadotropin-releasing hormone (GnRH).
Frequently asked questions
Is Gonadorelin FDA-approved?
FDA-approved (diagnostic; Factrel®) On Jevity's evidence scale, Gonadorelin is graded "FDA-approved". Reclassification for compounding is not the same as FDA approval.
What is Gonadorelin used for?
A natural-sequence GnRH used to stimulate the body's own hormone production. Pulses the pituitary to release LH/FSH, supporting testosterone/fertility pathways. Studied effects include: Supports natural hormone production; Used alongside some TRT protocols. This is educational information, not a recommendation to use it.
Is Gonadorelin legal in the UAE?
UAE / DHA status: Prescription medicine — DHA-licensed provider
Is Gonadorelin banned in sport?
WADA status: Not prohibited
What is Gonadorelin's Jevity Score?
Gonadorelin has a Jevity Score of 88/100 — a proprietary composite of evidence strength (10/10), regulatory clarity (8/10) and supply verifiability (7/10). It reflects how established and legitimate the compound is, not a recommendation.
Related sexual & hormonal peptides
Educational information only — not medical advice, a diagnosis, or a recommendation to use any substance or therapy. Regulatory status changes; verify current rules and any personal decision with a licensed clinician. Jevity is operated by Upcapital Global FZCO, Dubai, UAE.