Longevity & cellular · Peptide
Humanin
A mitochondrial-derived peptide associated with cellular protection and longevity.
Status as of 2026-07 · reclassification ≠ FDA approval · educational only, not medical advice.
The signal it sends
Activates cell-survival/anti-apoptotic signaling; levels correlate with healthy aging.
Benefits & effects studied
- Cytoprotective signals
- Neuro- & cardio-protective interest
Research state
Active longevity science; not a treatment.
Dosing & pharmacokinetics
Investigational. Half-life: Short.
Dosing information is educational only. Humanin decisions belong with a licensed clinician — Jevity does not recommend or supply dosing.
History & discovery
First described 2001 by Nishimoto Lab (also independently found by two other labs) Origin: Discovered in 2001 by the Nishimoto lab via screening of a cDNA library from the relatively spared occipital lobe of an Alzheimer's patient, while searching for factors that protect neurons from amyloid-beta toxicity; it was the first mitochondria-derived peptide identified..
Molecular structure
A 24-amino-acid mitochondrial-derived peptide encoded within the 16S ribosomal RNA gene of mitochondrial DNA.
Frequently asked questions
Is Humanin FDA-approved?
Not FDA-approved — preclinical On Jevity's evidence scale, Humanin is graded "Animal data only". Reclassification for compounding is not the same as FDA approval.
What is Humanin used for?
A mitochondrial-derived peptide associated with cellular protection and longevity. Activates cell-survival/anti-apoptotic signaling; levels correlate with healthy aging. Studied effects include: Cytoprotective signals; Neuro- & cardio-protective interest. This is educational information, not a recommendation to use it.
Is Humanin legal in the UAE?
UAE / DHA status: Not available — investigational
Is Humanin banned in sport?
WADA status: Verify on current WADA list
What is Humanin's Jevity Score?
Humanin has a Jevity Score of 25/100 — a proprietary composite of evidence strength (2/10), regulatory clarity (3/10) and supply verifiability (3/10). It reflects how established and legitimate the compound is, not a recommendation.
Humanin is prescription-only or research-only. A licensed clinician must evaluate whether it's appropriate for you.
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Educational information only — not medical advice, a diagnosis, or a recommendation to use any substance or therapy. Regulatory status changes; verify current rules and any personal decision with a licensed clinician. Jevity is operated by Upcapital Global FZCO, Dubai, UAE.