Cognitive & mood · Peptide
Dihexa
A potent synaptogenic compound studied for memory and neural connections.
Status as of 2026-07 · reclassification ≠ FDA approval · educational only, not medical advice.
The signal it sends
Amplifies hepatocyte-growth-factor signaling to promote new synapse formation.
Benefits & effects studied
- Synapse-formation research
- Memory interest (pre-clinical)
Research state
Pre-clinical; very limited human data. Not approved.
Dosing & pharmacokinetics
Investigational. Half-life: Unknown in humans.
Dosing information is educational only. Dihexa decisions belong with a licensed clinician — Jevity does not recommend or supply dosing.
History & discovery
First described late 2000s by Joseph Harding and John Wright (Washington State University) Origin: Developed in the late 2000s by Joseph Harding and John Wright at Washington State University, emerging from a research program (begun in the 1990s) on the procognitive effects of angiotensin IV; they created metabolically stabilized, brain-penetrant analogs of that scaffold (also called PNB-0408)..
Molecular structure
A synthetic small oligopeptide derivative of angiotensin IV, engineered for oral bioavailability and blood-brain-barrier penetration.
Frequently asked questions
Is Dihexa FDA-approved?
Not FDA-approved — early research On Jevity's evidence scale, Dihexa is graded "Animal data only". Reclassification for compounding is not the same as FDA approval.
What is Dihexa used for?
A potent synaptogenic compound studied for memory and neural connections. Amplifies hepatocyte-growth-factor signaling to promote new synapse formation. Studied effects include: Synapse-formation research; Memory interest (pre-clinical). This is educational information, not a recommendation to use it.
Is Dihexa legal in the UAE?
UAE / DHA status: Not available — investigational
Is Dihexa banned in sport?
WADA status: Verify on current WADA list
What is Dihexa's Jevity Score?
Dihexa has a Jevity Score of 22/100 — a proprietary composite of evidence strength (2/10), regulatory clarity (2/10) and supply verifiability (3/10). It reflects how established and legitimate the compound is, not a recommendation.
Dihexa is prescription-only or research-only. A licensed clinician must evaluate whether it's appropriate for you.
Book a consult →Related cognitive & mood peptides
Educational information only — not medical advice, a diagnosis, or a recommendation to use any substance or therapy. Regulatory status changes; verify current rules and any personal decision with a licensed clinician. Jevity is operated by Upcapital Global FZCO, Dubai, UAE.